BDBM50511504 CHEMBL4589737

SMILES [H][C@]12Cc3ccc(OC)c(OC)c3-c3ccc(C)c(CCN1C)c23

InChI Key InChIKey=AVUWEGVPHVPZJZ-MRXNPFEDSA-N

Data  6 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50511504   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataEC50:  2.56E+3nMAssay Description:Agonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataEC50:  2.57E+3nMAssay Description:Agonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataIC50:  1.41E+3nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataEC50:  87nMAssay Description:Agonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP Glo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataIC50:  1.43E+3nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataIC50:  3.63E+3nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataEC50:  87nMAssay Description:Agonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP Glo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataIC50:  3.63E+3nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511504(CHEMBL4589737)
Affinity DataEC50:  0.794nMAssay Description:Agonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed