BDBM50511686 CHEMBL4468733
SMILES NC(=O)c1ccc(cc1)-c1cnn2ccc(NCc3ccccn3)nc12
InChI Key InChIKey=OSHIEAFPXASVQE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50511686
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Manchester
Curated by ChEMBL
University of Manchester
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant N-Terminal GST-tagged human RET V804M mutant (658 to end residues) incubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Manchester
Curated by ChEMBL
University of Manchester
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of RET V804M mutant (unknown origin)expressed in human BaF3 cells assessed as reduction in cell viability incubated for 48 hrs by celltite...More data for this Ligand-Target Pair