BDBM50512185 CHEMBL4461347

SMILES CC(c1nc(no1)-c1ccncc1)n1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CC[C@@H](CN)C1

InChI Key InChIKey=VRWUBSSUSJURIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512185   

TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512185(CHEMBL4461347)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed