BDBM50512196 CHEMBL4457484

SMILES CNCCCCNc1cc2n(Cc3ccc(cc3)-c3ccccc3)cc(C(O)=O)c(=O)c2cc1F

InChI Key InChIKey=KZJKUPSDLGJCCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512196   

TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512196(CHEMBL4457484)
Affinity DataIC50: 8.83E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed