BDBM50512204 CHEMBL4563149

SMILES COc1c(NCCN)c(F)cc2c1n(Cc1ccc(cc1)-c1ccccc1)cc(C(O)=O)c2=O

InChI Key InChIKey=KQVJYODEISHNPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512204   

TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512204(CHEMBL4563149)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed