BDBM50512215 CHEMBL4550067

SMILES [H][C@@]12CN(C[C@]1([H])CNCC2)c1cc2n(Cc3ccc(cc3)-n3cccn3)cc(C(O)=O)c(=O)c2cc1F

InChI Key InChIKey=MDDMYSXROBZKPE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512215   

TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512215(CHEMBL4550067)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed