BDBM50512808 CHEMBL4438361

SMILES CCCCN1CCN(CC1)c1ccccc1OCCF

InChI Key InChIKey=MPRKJVQRTVEJJH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50512808   

TargetD(3) dopamine receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50512808(CHEMBL4438361)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]IABN from recombinant human D3 receptor stably expressed in HEK293 cell membranes measured after 60 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512808(CHEMBL4438361)
Affinity DataKi:  15nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D2L receptor expressed in HEK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50512808(CHEMBL4438361)
Affinity DataKi:  22nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D3 receptor expressed in HEK2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50512808(CHEMBL4438361)
Affinity DataKi:  22nMAssay Description:Displacement of [125I]IABN from recombinant human D2 long receptor stably expressed in HEK293 cell membranes measured after 60 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50512808(CHEMBL4438361)
Affinity DataIC50: 678nMAssay Description:Binding affinity to human D3 receptor expressed in CHO-K1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed