BDBM50512920 CHEMBL4578760

SMILES Cc1cc(-c2cc[nH]n2)ccc1C(=O)[C@@H]1CCCC[C@H]1C(=O)Nc1cn(C)nc1C

InChI Key InChIKey=AYZQVGPXECKJJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512920   

LigandChemical structure of BindingDB Monomer ID 50512920BDBM50512920(CHEMBL4578760)
Affinity DataIC50: 794nMAssay Description:Inhibition of FLAP in human whole blood assessed as reduction in calcium ionophore-stimulated LTB4 production preincubated for 30 mins followed by ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50512920BDBM50512920(CHEMBL4578760)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]MK0591 binding to human FLAP expressed in human COS7 cell membranes measured after 60 to 80 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed