BDBM50512922 CHEMBL4533700
SMILES O=C(Nc1cnn2cccnc12)[C@@H]1CCCC[C@H]1C(=O)c1ccc(cc1)-c1cc[nH]n1
InChI Key InChIKey=MJJOCVSZEMTHJQ-QZTJIDSGSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50512922
Affinity DataIC50: 40nMAssay Description:Inhibition of FLAP in human whole blood assessed as reduction in calcium ionophore-stimulated LTB4 production preincubated for 30 mins followed by ca...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]MK0591 binding to human FLAP expressed in human COS7 cell membranes measured after 60 to 80 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: <3.16E+4nMAssay Description:Inhibition of human ERG by high-throughput electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of CYP450 assessed as maximum reduction in metabolite formation using coumarin based substrate by fluorescence assayMore data for this Ligand-Target Pair