BDBM50513221 CHEMBL4455013

SMILES COc1ccc(CNC(=O)C2CCN(CC2)C(=O)c2ccccc2)cc1OC

InChI Key InChIKey=OJODVAHCAIUCKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513221   

TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50513221(CHEMBL4455013)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by UV-visible absorption methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50513221(CHEMBL4455013)
Affinity DataIC50: 18nMAssay Description:Inhibition of BACE-1 (unknown origin) after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed