BDBM50513356 CHEMBL4483780

SMILES CN1CCC(CC1)c1cnn(c1)-c1nccc2c1nc[nH]c2=O

InChI Key InChIKey=WDLBUONJQGHSKT-UHFFFAOYSA-N

Data  4 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50513356   

TargetLysine-specific demethylase 5C(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513356(CHEMBL4483780)
Affinity DataIC50:  163nMAssay Description:Inhibition of KDM5C (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513356(CHEMBL4483780)
Affinity DataIC50:  820nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4A(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513356(CHEMBL4483780)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific demethylase 5B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513356(CHEMBL4483780)
Affinity DataIC50:  156nMAssay Description:Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)