BDBM50514413 CHEMBL4555061

SMILES OC(=O)c1nonc1NCn1nnnc1Cc1ccccc1

InChI Key InChIKey=PUTXFHUYYIJFOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514413   

TargetSignal transducer and activator of transcription 5B(Mus musculus)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514413(CHEMBL4555061)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514413(CHEMBL4555061)
Affinity DataIC50:  2.90E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed