BDBM50514996 CHEMBL4587332

SMILES Nc1nc2[nH]c(CCNC(=O)c3cccc(C(=O)NCc4ccccn4)c3)cc2c(=O)[nH]1

InChI Key InChIKey=PCMQZZYOBBXXFL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514996   

TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514996BDBM50514996(CHEMBL4587332)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed