BDBM50515198 CHEMBL4445573
SMILES C[C@H]1COCCN1c1nc(nc(n1)-c1cnc(N)nc1C(F)F)N1CCOCC1
InChI Key InChIKey=BSJSHEXWIGDLOO-JTQLQIEISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50515198
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant N-terminal His6-tagged PI3K p110alpha (unknown origin) incubated for 1 hr by FR...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of Alexafluor labelled kinase tracer314 from recombinant human C-terminal GST-tagged mTOR (1360 to 2549 amino acids) expressed in insect...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of mTORC1 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of Hradec Kralove
Curated by ChEMBL
University of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair