BDBM50515333 CHEMBL4460815
SMILES Fc1ccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)cc1
InChI Key InChIKey=XQMFLUIVLXDXEJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50515333
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataKi: 81nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.32E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataEC50: 520nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair