BDBM50515640 CHEMBL4532127

SMILES CC1(C)[C@H]2CC[C@@]1(C)C(NC(=O)C(c1c(C(=O)O)[nH]c3cc(Cl)ccc13)N(C=O)Cc1ccc(OCc3ccccc3Br)cc1)C2

InChI Key InChIKey=OMUYGOGGWRFGKD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515640   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515640BDBM50515640(CHEMBL4532127)
Affinity DataKi:  6nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515640BDBM50515640(CHEMBL4532127)
Affinity DataKi:  1.95E+3nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant MDMX (18 to 111 residues) expressed in Escherichia coli BL21 (DE3) cells measured after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed