BDBM50515978 CHEMBL1967497

SMILES COc1ccc2nc(C)cc(N\N=C\c3cccc(OC)c3O)c2c1

InChI Key InChIKey=AULQYWKIJVZYFH-RGVLZGJSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50515978   

TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50515978(CHEMBL1967497)
Affinity DataIC50:  7.34E+4nMAssay Description:Inhibition of recombinant human NQO1 expressed in Escherichia coli using DCPIP as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50515978(CHEMBL1967497)
Affinity DataIC50:  440nMAssay Description:Inhibition of NQO2 in human SKOV3 cells assessed as reduction in cell viability in presence of 1 uM CB1954 and EPR incubated for 24 hrs measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50515978(CHEMBL1967497)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human NQO2 expressed in Escherichia coli using DCPIP as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed