BDBM50516234 CHEMBL4470048

SMILES COc1cc(OC)cc(c1)C(=O)NCCNC(=O)[C@H](CC(=O)NC(C)(C)C)NS(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=VHIHNBOGWAAAMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516234   

TargetProteasome subunit beta type-8(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50516234(CHEMBL4470048)
Affinity DataIC50: 9.97E+3nMAssay Description:Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50516234(CHEMBL4470048)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human beta5 20S constitutive proteasome using suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed