BDBM50516382 CHEMBL4436895

SMILES Fc1cccc(Br)c1C(=O)c1c[nH]c(c1)C(=O)Nc1cccnc1

InChI Key InChIKey=ATKCERYALDNMPL-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50516382   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50516382(CHEMBL4436895)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50516382(CHEMBL4436895)
Affinity DataIC50:  820nMAssay Description:Inhibition of recombinant N-terminal His-tagged human ERK5 (2 to 409 residues) co-expressed with GST-tagged human truncated MEK5DD lacking N-terminal...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50516382(CHEMBL4436895)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50516382(CHEMBL4436895)
Affinity DataIC50:  820nMAssay Description:Inhibition of human recombinant N-terminal His-tagged / TEV cleavage site fused ERK5 (2 to 409 residues) expressed in baculovirus infected Sf9 cells ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50516382(CHEMBL4436895)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50516382(CHEMBL4436895)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of HA-tagged ERK5 (unknown origin) coexpressed with mutationally activated EGFP-MEK5D and Gal4-MEF2D in HEK293 cells assessed as reduction...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50516382(CHEMBL4436895)
Affinity DataIC50: >1.20E+5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full length human p38alpha expressed in Escherichia coli cells assessed as substrate phosphorylation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50516382(CHEMBL4436895)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed