BDBM50516935 CHEMBL4526073

SMILES CC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12

InChI Key InChIKey=AJGIAOZUTGDMKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516935   

TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50516935(CHEMBL4526073)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFR expressed in Escherichia coli BL21(DE3) assessed as reduction in consumption of NADPH using DHF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50516935(CHEMBL4526073)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50516935(CHEMBL4526073)
Affinity DataIC50: 9.80E+5nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed