BDBM50517059 CHEMBL4535842

SMILES COc1ccc(cc1OC)N1N=C(C)C(C(=O)Nc2cccc(c2)C(C)(F)F)C1=O

InChI Key InChIKey=ZAXTYABCDPAXMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517059   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50517059(CHEMBL4535842)
Affinity DataIC50:  1nMAssay Description:Inhibition of ACSS2 in human MDA-MB-468 cells assessed as 13C-acetate incorporation incubated for 5 hrs measured under hypoxic conditions by LCMS ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed