BDBM50517286 CHEMBL4516798

SMILES COc1ccccc1-c1n[nH]c2nc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)CCC(F)(F)F)nc(OC)c12

InChI Key InChIKey=UMNCFEICPGXRSJ-HDJSIYSDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517286   

TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50517286(CHEMBL4516798)
Affinity DataIC50:  6.31E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50517286(CHEMBL4516798)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed