BDBM50517556 CHEMBL4518390

SMILES COc1c([C@@H]2c3ccc4[nH]ncc4c3C[C@@H](C)N2CC(C)(F)F)ccc(/C=C/C(=O)O)c1F

InChI Key InChIKey=JEIAHMFXVQYONO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517556   

TargetEstrogen receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517556BDBM50517556(CHEMBL4518390)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to recombinant human GST-tagged ERalpha LBD expressed in baculovirus-infected insect cells by lantha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517556BDBM50517556(CHEMBL4518390)
Affinity DataIC50: 6.30nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by in multiplexed cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed