BDBM50517560 CHEMBL4583286

SMILES COc1cc(/C=C/C(=O)O)cc(F)c1[C@@H]1c2ccc3[nH]ncc3c2C[C@@H](C)N1CC(C)(F)F

InChI Key InChIKey=JJBSVWGUVMRJFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517560   

TargetEstrogen receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517560BDBM50517560(CHEMBL4583286)
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by in multiplexed cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517560BDBM50517560(CHEMBL4583286)
Affinity DataIC50: 0.316nMAssay Description:Binding affinity to recombinant human GST-tagged ERalpha LBD expressed in baculovirus-infected insect cells by lantha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed