BDBM50517611 CHEMBL4544868

SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](C[C@@H]2CCCC3CCCCC23)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=IJXUVRJYZJRYCL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50517611   

TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517611BDBM50517611(CHEMBL4544868)
Affinity DataIC50: 380nMAssay Description:Inhibition of 20S immunoproteasome beta 2 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517611BDBM50517611(CHEMBL4544868)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517611BDBM50517611(CHEMBL4544868)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 20S immunoproteasome beta 1 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517611BDBM50517611(CHEMBL4544868)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 20S immunoproteasome beta 5 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517611BDBM50517611(CHEMBL4544868)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 20S constitutive proteasome beta 1 caspase-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517611BDBM50517611(CHEMBL4544868)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 20S constitutive proteasome beta 5 chymotrypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed