BDBM50517735 CHEMBL4472945

SMILES COc1ccccc1C(=O)OCc1ccccc1-n1cc(CNC(=O)N[C@@H](CC(C)C)C(=O)NO)nn1

InChI Key InChIKey=DUUIIYSIDUKKQO-FQEVSTJZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50517735   

TargetAminopeptidase N(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50517735(CHEMBL4472945)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of APN on human PLC/PRF/5 cell surface using L-Leu-p-nitroanilide as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50517735(CHEMBL4472945)
Affinity DataIC50:  990nMAssay Description:Inhibition of APN on human ES-2 cell surface using L-Leu-p-nitroanilide as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50517735(CHEMBL4472945)
Affinity DataIC50:  160nMAssay Description:Inhibition of porcine kidney microsomal APN using L-Leu-p-nitroanilide as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed