BDBM50518021 CHEMBL610279

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2cc(NC(N)=N)ccc12)ccc3O

InChI Key InChIKey=XDKOGAAFSBGLBO-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50518021   

TargetKappa-type opioid receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518021(CHEMBL610279)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at full-length Renilla luciferase 8 fused with c-terminal human kappa opioid receptor expressed in HEK293T cells assessed as inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518021(CHEMBL610279)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human KOR receptor stably expressed in HEK293 cells assessed as inhibition constant by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518021(CHEMBL610279)
Affinity DataEC50:  1.60nMAssay Description:Partial agonist activity at full-length Renilla luciferase 8 fused with c-terminal human kappa opioid receptor expressed in HEK293T cells assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50518021(CHEMBL610279)
Affinity DataKi:  20nMAssay Description:Binding affinity to human MOR expressed in HEK293 cells assessed as inhibition constant by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50518021(CHEMBL610279)
Affinity DataKi:  82nMAssay Description:Binding affinity to human DOR expressed in HEK293 cells assessed as inhibition constant by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed