BDBM50518209 CHEMBL4548691

SMILES OC(=O)[C@H]1CNC[C@H](C1)N\N=C\c1ccccc1-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=HUJFQLHFKOTVSD-GSTCZNPNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518209   

TargetSodium- and chloride-dependent GABA transporter 3(Human)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50518209(CHEMBL4548691)
Affinity DataIC50:  9.33E+3nMAssay Description:Inhibition of human GAT3 expressed in COS7 cells assessed as reduction in [2H6]GABA uptake preincubated for 25 mins followed by [2H6]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50518209(CHEMBL4548691)
Affinity DataIC50:  6.61E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK cells assessed as reduction in [3H]GABA uptake by measuring remaining [3H]GABA uptake levels preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50518209(CHEMBL4548691)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of mouse GAT4 expressed in HEK cells assessed as reduction in [3H]GABA uptake by measuring remaining [3H]GABA uptake levels preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed