BDBM50518609 CHEMBL4571215
SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc12)C(=O)c1nc2ccccc2s1
InChI Key InChIKey=DDDBXZXECGEQRK-SVBPBHIXSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50518609
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged matriptase catalytic domain expressed in Escherichia coli preincubated for 30 mins followed by...More data for this Ligand-Target Pair
TargetSerine protease hepsin(Homo sapiens (Human))
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataKi: 391nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged hepsin catalytic domain preincubated for 30 mins followed by Boc-QAR-AMC substrate addition a...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair