BDBM50518801 CHEMBL4470091

SMILES c1ccc2cc(ccc2c1)S(=O)(=O)NNC(=O)c3ccccc3F

InChI Key InChIKey=CMGWGSMHPCWLOH-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50518801   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Cancer Therapeutics Crc

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 490nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 490nMAssay Description:Inhibition of KAT6A (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone acetyltransferase KAT7(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant human KAT7 catalytic domain using H3 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone acetyltransferase KAT6B(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 690nMAssay Description:Inhibition of full length recombinant human KAT6B catalytic domain using H4 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone acetyltransferase KAT6A [507-778](Human)
Cancer Therapeutics Crc

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT5(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of full length recombinant human KAT5 catalytic domain using H2A peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone acetyltransferase KAT8(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of full length recombinant human KAT8 catalytic domain using H4 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A [507-778](Human)
Cancer Therapeutics Crc

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 15 uM acetyl c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT7(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of KAT7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT5(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of KAT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed