BDBM50519165 CHEMBL4516070

SMILES CC[N@+]1(C[C@@H](CC([O-])=O)c2cccc(c2)-n2nc(C)cc2C)CC[C@@H](CCc2ccc3CCCNc3n2)C1

InChI Key InChIKey=ZHDLQWCRZPIIAQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50519165   

TargetIntegrin alpha-V/beta-6(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519165(CHEMBL4516070)
Affinity DataIC50: 40nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-8(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519165(CHEMBL4516070)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of integrin alphavbeta8 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519165(CHEMBL4516070)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of integrin alphavbeta1 (unknown origin) expressed in human A549 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519165(CHEMBL4516070)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of integrin alphavbeta5 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to human vitronectin incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed