BDBM50519753 CHEMBL4526845

SMILES Oc1cccc2cc(-c3ccc(Br)cc3)c(=O)oc12

InChI Key InChIKey=HHVNBOHWALFNHB-UHFFFAOYSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50519753   

TargetAdenosine receptor A3(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataKi:  258nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]CCPA from human adenosine A1A receptor expressed in CHO cells measured by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A3(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human adenosine receptor A3 expressed in CHO cells assessed as suppression of NECA-induced decrease of cAMP accumulation by Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human adenosine A3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A3(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataKi:  3.85E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine A3 receptor expressed in CHO cells measured by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataKi:  1.21E+4nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cells measured by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2b(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of radioligand from human adenosine receptor A2B expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human adenosine receptor A2B expressed in CHO cells assessed as suppression of NECA-induced decrease of cAMP accumulation by G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50519753(CHEMBL4526845)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed