BDBM50520522 CHEMBL4568628

SMILES COc1cc(NC(=O)[C@@H](Cc2ccccc2)NC2=C\C(=N\O)c3ccccc3C2=O)cc(OC)c1

InChI Key InChIKey=BTNMSAUAXSTYIU-UHFFFAOYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50520522   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50520522(CHEMBL4568628)
Affinity DataKd:  0.00450nMAssay Description:Binding affinity to recombinant human IDO1 assessed as kinetic dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50520522(CHEMBL4568628)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human IDO1 using L-tryptophan as substrate incubated under dark conditions measured after 60 mins by fluorescence microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50520522(CHEMBL4568628)
Affinity DataKd:  80nMAssay Description:Binding affinity to recombinant human IDO1 assessed as equilibrium dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50520522(CHEMBL4568628)
Affinity DataKd:  530nMAssay Description:Binding affinity to STAT3 in human SKOV3 cells assessed as equilibrium dissociation constant after 200 sec by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed