BDBM50520759 CHEMBL4546979

SMILES CC(Oc1ccc(Oc2ccc(F)cc2)cc1)C(=O)Cn1nnc(n1)-c1ccccc1

InChI Key InChIKey=BJRSWSMLWOGTOZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50520759   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50520759(CHEMBL4546979)
Affinity DataIC50: 24nMAssay Description:Inhibition of FAAH in rat brain microsomes using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate after 60 mins by fluorescence-based HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50520759(CHEMBL4546979)
Affinity DataIC50: 29nMAssay Description:Inhibition of FAAH in rat liver S9 fraction using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate preincubated for 45 mins in absence of NADPH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50520759(CHEMBL4546979)
Affinity DataIC50: 31nMAssay Description:Inhibition of FAAH in rat liver S9 fraction using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate after 60 mins by fluorescence-based HPLC ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50520759(CHEMBL4546979)
Affinity DataIC50: 89nMAssay Description:Inhibition of FAAH in rat brain microsomes using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate after 5 mins by fluorescence-based HPLC analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50520759(CHEMBL4546979)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of FAAH in rat liver S9 fraction using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate preincubated for 15 mins followed by NADPH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed