BDBM50520826 CHEMBL4545086

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cccnc12

InChI Key InChIKey=SLWGAMHEUFJZOW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50520826   

TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520826(CHEMBL4545086)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant (696-end residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520826(CHEMBL4545086)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in baculovirus expression system by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520826(CHEMBL4545086)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (696-end residues) expressed in baculovirus expression system using Srctide as substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed