BDBM50521059 CHEMBL4449979

SMILES COc1cc(cc(c1)C(F)(F)F)C(=O)Nc1nnc(o1)C1CCCCC1

InChI Key InChIKey=PYUNGAFBELDMDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521059   

TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50521059(CHEMBL4449979)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human AC1 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50521059(CHEMBL4449979)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed