BDBM50521068 CHEMBL4476423

SMILES Clc1ccc2oc(cc(=O)c2c1)C(Cl)(Cl)Cl

InChI Key InChIKey=NTDHYMSVCBGQJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50521068   

TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521068BDBM50521068(CHEMBL4476423)
Affinity DataIC50: 300nMAssay Description:Inhibition of adenylyl cyclase 1 (unknown origin) transfected in HEK293 cells assessed as reduction in A23187-induced cAMP accumulation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521068BDBM50521068(CHEMBL4476423)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of AC1 (unknown origin) expressed in HEK cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521068BDBM50521068(CHEMBL4476423)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of adenylyl cyclase 8 (unknown origin) transfected in HEK293 cells assessed as reduction in A23187-induced cAMP accumulation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed