BDBM50521267 CHEMBL4513748

SMILES COc1ccc(F)c(c1)[C@H]1CC[C@H](COc2cccc(c2)[C@@H]([C@@H](C)C(O)=O)C2CC2)CC1

InChI Key InChIKey=HIZJLJKRIIOELO-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50521267   

TargetFree fatty acid receptor 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521267(CHEMBL4513748)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by Fluo-8 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521267(CHEMBL4513748)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by Fluo-8 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521267(CHEMBL4513748)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human GPR40 expressed in CHOK1 cells assessed as induction of Galphaq-mediated IP1 accumulation after 90 mins HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed