BDBM50521923 CHEMBL4438971

SMILES COCCN1CCC(CC1)Nc1nccc(n1)-c1cn[nH]c1C(C)C

InChI Key InChIKey=GRHFKIYSAMODSD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50521923   

LigandPNGBDBM50521923(CHEMBL4438971)
Affinity DataKi:  20nMAssay Description:Inhibition of human full length GST-tagged CDK4 (1 to 303(end) amino acids)/Cyclin D3 (1 to 292(end) amino acids) expressed in baculovirus expression...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50521923(CHEMBL4438971)
Affinity DataKi:  270nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50521923(CHEMBL4438971)
Affinity DataKi:  320nMAssay Description:Inhibition of human full length GST-tagged CDK2 (1 to 298(end) amino acids)/Cyclin E1 (1 to 410(end) amino acids) expressed in baculovirus expression...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50521923(CHEMBL4438971)
Affinity DataKi:  720nMAssay Description:Inhibition of human full length GST-tagged CDK6 (1 to 326(end) amino acids)/Cyclin D3 (1 to 292(end) amino acids) expressed in baculovirus expression...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed