BDBM50522001 CHEMBL4526382

SMILES Cl.Cl.CN1CCN(CC1)c1sc(NC(=O)c2cnn(Cc3ccc(F)cc3)c2C)nc1C1CCC1

InChI Key InChIKey=VXZYLZYWYXAAHK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522001   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50522001(CHEMBL4526382)Copy SMILESCopy InChI

Affinity DataIC50:  30nMAssay Description:Inhibition of human TRPV4 expressed in HEK293 cells assessed as reduction in Ca2+ influx incubated for 30 mins by Fluo4-AM dye basedMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI