BDBM50522400 CHEMBL4562342

SMILES C[C@@]1(c2ccc(Cl)cc2Cl)OC[C@@H](COc2ccc(N3CCN(c4ccc(-n5cn[nH]c5=O)cc4)CC3)cc2)O1

InChI Key InChIKey=YHGHBAXLVHCABI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522400   

TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522400BDBM50522400(CHEMBL4562342)
Affinity DataIC50: 140nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed