BDBM50522507 CHEMBL4470852
SMILES CN1Cc2cc(Nc3ncc4c(n3)[nH]cc(-c3c(Cl)cccc3Cl)c4=O)ccc2C2(CC2)C1
InChI Key InChIKey=FWAVUQBDZHENIR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50522507
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 29nMAssay Description:Inhibition of WEE1 in human NCI-H1299 cells assessed as reduction in Cdc2 phosphorylation at Tyr15 residue measured after 6 hrs by ELISAMore data for this Ligand-Target Pair