BDBM50522560 CHEMBL4531228

SMILES Fc1ccc(cc1C(F)(F)F)S(=O)(=O)Nc1ccc2oc(nc2c1)-c1ccc(NS(=O)(=O)c2ccc(Cl)s2)cc1

InChI Key InChIKey=HGFBPMWHZSDSBS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50522560   

TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522560BDBM50522560(CHEMBL4531228)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged PtpB expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 30 mins by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522560BDBM50522560(CHEMBL4531228)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human PTPN1 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522560BDBM50522560(CHEMBL4531228)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human PTPN5 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50522560BDBM50522560(CHEMBL4531228)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PTPN2 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed