BDBM50522748 CHEMBL4531337

SMILES Cc1cc(ccc1F)-c1cnc(N)c(c1)C(=O)Nc1c(C)cccc1Cl

InChI Key InChIKey=NWDFFSNVVNEJMS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522748   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50522748(CHEMBL4531337)
Affinity DataEC50:  3.34E+3nMAssay Description:Positive allosteric modulation activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50522748(CHEMBL4531337)
Affinity DataEC50:  2.58E+5nMAssay Description:Positive allosteric modulation activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed