BDBM50522753 CHEMBL4514758

SMILES COc1cc(O)c(Cl)c(C)c1-c1cc(O)c(Cl)c2cc3c(C(=O)c4c(O)cc(O)cc4C3(C)C)c(O)c12

InChI Key InChIKey=OQDPQNIEZGGSQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522753   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50522753(CHEMBL4514758)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522753(CHEMBL4514758)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed