BDBM50523050 CHEMBL4455953

SMILES CC1=C([C@@H](Oc2c(O)cccc12)c1ccc(OCCN2CC(CF)C2)cc1)c1cccc(O)c1

InChI Key InChIKey=UEGMBSNOWSMURK-MHZLTWQESA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523050   

TargetEstrogen receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL

LigandBDBM50523050(CHEMBL4455953)Copy SMILESCopy InChI

Affinity DataIC50:  0.0500nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI
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TargetEstrogen receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL

LigandBDBM50523050(CHEMBL4455953)Copy SMILESCopy InChI

Affinity DataIC50:  0.0500nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI
Copy reaction URL