BDBM50523585 CHEMBL4577468

SMILES OC(=O)c1ccc(CNc2ccc(cn2)-c2ccc(cn2)-c2nc3cc(Cl)ccc3[nH]2)cc1

InChI Key InChIKey=KMRKVWIQPVPEED-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50523585   

LigandPNGBDBM50523585(CHEMBL4577468)
Affinity DataKi:  1.19E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523585(CHEMBL4577468)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523585(CHEMBL4577468)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50523585(CHEMBL4577468)
Affinity DataIC50:  84nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523585(CHEMBL4577468)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed