BDBM50523703 CHEMBL4560057

SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)ccc1N

InChI Key InChIKey=WLRRDZZLCUZBHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523703   

TargetSerine/threonine-protein kinase B-raf(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50523703(CHEMBL4560057)
Affinity DataIC50: 165nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged BRAF V600E mutant catalytic domain (416 to 766 residues) expressed in baculovirus expression sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50523703(CHEMBL4560057)
Affinity DataIC50: 7.11E+3nMAssay Description:Inhibition of recombinant full-length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Fluor-de-Lys as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed