BDBM50523714 CHEMBL4457019

SMILES CN(C)C(=O)c1cc(Oc2ccc(NC(=O)c3ccc(Cl)c(c3)C(F)(F)F)cc2)ccc1N

InChI Key InChIKey=QEWBFAXRQXNGRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523714   

TargetSerine/threonine-protein kinase B-raf(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50523714(CHEMBL4457019)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged BRAF V600E mutant catalytic domain (416 to 766 residues) expressed in baculovirus expression sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50523714(CHEMBL4457019)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50523714(CHEMBL4457019)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed