BDBM50523787 CHEMBL4464347

SMILES COC(=O)[C@H](Cc1cn(cn1)C(c1ccccc1)(c1ccccc1)c1ccccc1)NCc1cc(ccn1)N(C)C

InChI Key InChIKey=KWEWTRANJHEQQI-YTTGMZPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523787   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50523787(CHEMBL4464347)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using RHKK(Ac)-MCA as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50523787(CHEMBL4464347)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed